According to this video on Gear Live (check it out soon as I'm sure it'll be taken down any moment now), it looks like Uno will be the first game to support the XBox 360 Camera.

The one disapointing thing that the video shows though is that Texas Hold'em, a game that would have more to gain from it, doesn't support it.

Xboxyde has some screenshots from the debug version of the live arcade's Uno. Looks good and hopefully it means the game will be released soon.

Check them out here

Here is the first of the new (hopefully) weekly features, there will be more features coming down the pipe, but all in good time. Anyways, here is this weeks rumor roundup…
Uno to be developed by Silver Creek Entertainment.
Rumor: When the announcement came out that one of the next games to be released came out of the blue, the rumor mill started turning about who the developer could be. Many sites (this one included) figured that it would have to be the only dev to release any card games to date, Silver Creek Entertainment.
Our Take: We were wrong. According to this post here, Silver Creek has nothing to do with Uno, so were still left guessing as to who it’ll be.
No Rare owned properties will be on the Revolution Virtual Console
Rumor: None of Rare’s IP, including Goldeneye and Killer Instinct will be making it’s way to big “N”s virtual console.
Our Take: Did anyone actually think that this would ever happen? The real question is which of them will make there way to XBLA?

According to this quote found on Eurogamer
It also reiterated that Street Fighter II: Hyper Fighting, Uno and Texas Hold ‘Em Poker will be out on Xbox Live Arcade - given the “this is our spring line-up ZOMG” style of the press release, presumably quite soon.
Microsoft has let a couple cats out of the bag. First it seems that earlier rumors were incorrect about a delay for Street Fighter and also, a version of Uno is on it’s way. While who is creating Uno is unannounced, a good bet would be Silver Creek Entertainment, makers of the Hardwood Series.